Kaiser Fung of the newly (re)launched FiveThirtyEight on using airfare prediction software to find the lowest price:
In the end, even though my analysis shows that you might not save any money following Kayak’s algorithm as opposed to buying tickets two weeks ahead of your scheduled departure, it still might be worth your time and energy to use airfare prediction software. Why? Because following the algorithm isn’t going to cost you more money, and it might actually relieve some of the second-guessing that occurs when you’re left to your own devices.
Airfare Prediction Software, such as Kayak’s, is one area I’ve never really paid much attention to, but if you regularly purchase flights for full price, I’d say it’s worth looking into.